Research shows that when you do things with your hands, whether cooking or gardening, crafting (OR QUILTING!), happy chemicals are released in your brain. (I think that's called dopamine:)
I've used 2 methods to enlarge a design. The first- use a printing service that has a Large-Format Printer. HP makes two widths, 24" and 36". Do your math, you may need to cut your design in 1/2 lengthwise to get 2 rolls with 1/2 your design on each roll.
Appliquéd the bicycle on first by cutting out the fabric pieces 1/4" larger than the template, ironing the edges under and sewing them on close the edge. Attach the basket the same way. Hyacinth Quilt Designs has a blog post with great pictures of this method.